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1

A Potent, Nonpeptidyl 1 H -Quinolone Antagonist for the Gonadotropin-Releasing Hormone Receptor

DeVita, Robert J., Walsh, Thomas F., Young, Jonathan R., Jiang, Jinlong, Ujjainwalla, Feroze, Toupence, Richard B., Parikh, Mamta, Huang, Song X., Fair, Jason A., Goulet, Mark T., Wyvratt, Matthew J.,

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 81 KB

english, 2001

2

Recommendations for end-of-life care in the intensive care unit: The Ethics Committee of the Society of Critical Care Medicine

Truog, Robert D., Cist, Alexandra F. M., Brackett, Sharon E., Burns, Jeffrey P., Curley, Martha A. Q., Danis, Marion, DeVita, Michael A., Rosenbaum, Stanley H., Rothenberg, David M., Sprung, Charles L

Journal:

Critical Care Medicine

Year:

2001

Language:

english

File:

PDF, 181 KB

english, 2001

3

Current controversies in critical care ethics: Not just end of life

DeVita, Michael A., Groeger, Jeffrey, Truog, Robert

Journal:

Critical Care Medicine

Year:

2003

Language:

english

File:

PDF, 185 KB

english, 2003

4

Gastric Lipoma

Chagarlamudi, Kaushik, Devita, Robert, Barr, Richard G.

Journal:

Ultrasound Quarterly

Year:

2018

Language:

english

File:

PDF, 263 KB

english, 2018

5

Rapidly destructive osteoarthritis of the hip

Matsunaga, Felipe, DeVita, Robert Russell, Young, Peter Christopher

Journal:

Internal and Emergency Medicine

Year:

2020

File:

PDF, 696 KB

2020

6

Hyaline fibromatosis syndrome: A rare case of multifocal intra-articular involvement

DeVita, Robert, Faraji, Navid, Nakfoor, Rachael, Elliott, Robin, Kosmas, Christos

Journal:

Clinical Imaging

Year:

2021

File:

PDF, 2.86 MB

2021

7

Physiologic disposition of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1-(2-chloroethyl)-3-(4-methyl cyclohexyl)-1-nitrosourea (MeCCNU) in man

Robert W. Sponzo, Vincent T. Devita, Vincent T. Oliverio

Journal:

Year:

1973

Language:

english

File:

PDF, 466 KB

english, 1973

8

Initial clinical trials with methyl-ccnu 1-(2-chloroethyl)-3-(4-methyl cyclohexyl)-1-nitrosourea (meccnu)

Robert C. Young, Michael D. Walker, George P. Canellos, Philip S. Schein, Bruce A. Chabner, Vincent T. Devita

Journal:

Year:

1973

Language:

english

File:

PDF, 434 KB

english, 1973

9

Combination versus single agent chemotherapy: A review of the basis for selection of drug treatment of cancer

Vincent T. Devita Jr, Robert C. Young, George P. Canellos

Journal:

Year:

1975

Language:

english

File:

PDF, 1.07 MB

english, 1975

10

Non-Hodgkin's lymphoma: Patterns of relapse from complete remission after combination chemotherapy

Dr. Philip S. Schein, Bruce A. Chabner, George P. Canellos, Robert C. Young, Vincent T. Devita Jr

Journal:

Year:

1975

Language:

english

File:

PDF, 323 KB

english, 1975

11

Perspectives on research in gynecologic oncology. Treatment protocols

Dr. Vincent T. Devita Jr., Todd H. Wasserman, Robert C. Young, Stephen K. Carter

Journal:

Year:

1976

Language:

english

File:

PDF, 1.47 MB

english, 1976

12

Combined modality treatment of American Burkittapos;s lymphoma

John L. Ziegler, Vincent T. Devita, Robert G. Graw Jr., Geoffrey Herzig, Brigid G. Leventhal, Arthur S. Levine, Thomas C. Pomeroy

Journal:

Year:

1976

Language:

english

File:

PDF, 539 KB

english, 1976

13

Diffuse histiocytic lymphoma involving the gastrointestinal tract

Dr. Kenneth R. Hande, Richard I. Fisher, Vincent T. Devita, Bruce A. Chabner, Robert C. Young

Journal:

Year:

1978

Language:

english

File:

PDF, 553 KB

english, 1978

14

Sequential nonsurgical and surgical staging of non-Hodgkin's lymphoma

Bruce A. Chabner, Ralph E. Johnson, Robert C. Young, George P. Canellos, Susan P. Hubbard, Sandra K. Johnson, Vincent T. Devita

Journal:

Year:

1978

Language:

english

File:

PDF, 291 KB

english, 1978

15

Hexamethylmelamine in alkylating agent-resistant ovarian carcinoma

Bonny L. Johnson, Richard I. Fisher, Richard A. Bender, Vincent T. Devita Jr., Bruce A. Chabner, Robert C. Young

Journal:

Year:

1978

Language:

english

File:

PDF, 435 KB

english, 1978

16

A comparison between combination chemotherapy and total body irradiation plus combination chemotherapy in non-Hodgkin's lymphoma

Harmar D. Brereton, Robert C. Young, Dan L. Longo, Leland R. Kirkland, Costan W. Berard, Elaine S. Jaffe, Vincent T. Devita, Ralph E. Johnson

Journal:

Year:

1979

Language:

english

File:

PDF, 329 KB

english, 1979

17

Natural history of malignant lymphomas with divergent histologies at staging evaluation

Richard I. Fisher, Roy B. Jones, Vincent T. Devita Jr., Richard M. Simon, A. Julian Garvin, Costan W. Berard, Robert C. Young

Journal:

Year:

1981

Language:

english

File:

PDF, 370 KB

english, 1981

18

Undifferentiated non-Hodgkin'S lymphomas (Burkitt's and non-Burkitt's types). The relevance of making this histologic distinction

John A. Miliauskas, Costan W. Berard, Robert C. Young, A. Julian Garvin, Brenda K. Edwards, Vincent T. Devita Jr.

Journal:

Year:

1982

Language:

english

File:

PDF, 1.07 MB

english, 1982

19

Malignant lymphoma II. Prognostic factors and response to treatment of 473 patients at the national cancer institute

Tom Anderson, Vincent T. Devita Jr., Richard M. Simon, Costan W. Berard, George P. Canellos, A. J. Garvin, Robert C. Young

Journal:

Year:

1982

Language:

english

File:

PDF, 1.20 MB

english, 1982

20

Malignant lymphoma I. The histology and staging of 473 patients at the national cancer institute

Tom Anderson, Bruce A. Chabner, Robert C. Young, Costan W. Berard, A. J. Garvin, Richard M. Simon, Vincent T. Devita Jr.

Journal:

Year:

1982

Language:

english

File:

PDF, 829 KB

english, 1982

21

ChemInform Abstract: Asymmetric Synthesis of Chiral, Nonracemic Trifluoromethyl-Substituted Piperidines and Decahydroquinolines.

Jinlong Jiang, Robert J. DeVita, George A. Doss, Mark T. Goulet, Matthew J. Wyvratt

Journal:

Year:

1999

File:

PDF, 35 KB

1999

22

ChemInform Abstract: Investigation of the 4-O-Alkylamine Substituent of Non-peptide Quinolone GnRH Receptor Antagonists.

Robert J. DeVita, Mark T. Goulet, Matthew J. Wyvratt, Michael H. Fisher, Jane-L. Lo, Yi Tien Yang, Kang Cheng, Roy G. Smith

Journal:

Year:

1999

File:

PDF, 30 KB

1999

23

Synthesis of 4-Trifluoromethylated 2-Alkyl- and 2,3-Dialkyl-Substituted Azetidines.

Jinlong Jiang, Hemal Shah, Robert J. DeVita

Journal:

Year:

2004

File:

PDF, 235 KB

2004

24

Synthesis of two non-peptidyl GnRH receptor antagonists via [14C]carbonylation

Charles S. Elmore, Dennis C. Dean, Robert J. DeVita, David G. Melillo

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2003

Language:

english

File:

PDF, 115 KB

english, 2003

25

Randomized comparison of chemotherapy (CVP) and radiotherapy (TBI) in stage III–IV poorly differentiated lymphocytic lymphoma

Ralph E. Johnson, George P. Canellos, Robert C. Young, Bruce A. Chabner, Vincent T. DeVita

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1978

Language:

english

File:

PDF, 77 KB

english, 1978

26

Tetrahydroindolizinone NK1 antagonists

Jianming Bao, Huagang Lu, Gregori J. Morriello, Emma J. Carlson, Alan Wheeldon, Gary G. Chicchi, Marc M. Kurtz, Kwei-Lan C. Tsao, Song Zheng, Xinchun Tong, Sander G. Mills, Robert J. DeVita

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 754 KB

english, 2010

27

Heterocyclic analogs of the benzolactam nucleus of the non-peptidic growth hormone secretagogue L-692,429

Robert J. DeVita, William R. Schoen, George A. Doldouras, Michael H. Fisher, Matthew J. Wyvratt Jr., Kang Cheng, Wanda W.-S. Chan, Bridget S. Butler, Roy G. Smith

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 294 KB

english, 1995

28

Fused bicyclic pyrrolizinones as new scaffolds for human NK1 antagonists

Gregori J. Morriello, Robert J. DeVita, Sander G. Mills, Jonathan R. Young, Peter Lin, George Doss, Gary G. Chicchi, Julie DeMartino, Marc M. Kurtz, Kwei-Lan C. Tsao, Emma Carlson, Karen Townson, Alan

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 276 KB

english, 2008

29

Syntheses and structure–activity relationship studies of piperidine-substituted quinolones as nonpeptide gonadotropin releasing hormone antagonists

Jinlong Jiang, Robert J. DeVita, Mark T. Goulet, Matthew J. Wyvratt, Jane-L. Lo, Ning Ren, Joel B. Yudkovitz, Jisong Cui, Yi T. Yang, Kang Cheng, Susan P. Rohrer

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 180 KB

english, 2004

30

The discovery of potent, selective, and orally bioavailable hNK1 antagonists derived from pyrrolidine

Peter Lin, Lehua Chang, Robert J. DeVita, Jonathan R. Young, Ronsar Eid, Xinchun Tong, Song Zheng, Richard G. Ball, Nancy N. Tsou, Gary G. Chicchi, Marc M. Kurtz, Kwei-Lan C. Tsao, Alan Wheeldon, Emma

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 425 KB

english, 2007

31

Pyrrolidine-carboxamides and oxadiazoles as potent hNK1 antagonists

Jonathan R. Young, Ronsar Eid, Cherilyn Turner, Robert J. DeVita, Marc M. Kurtz, Kwei-Lan C. Tsao, Gary G. Chicchi, Alan Wheeldon, Emma Carlson, Sander G. Mills

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 186 KB

english, 2007

32

Spiroimidazolidinone NPC1L1 inhibitors. 1: Discovery by 3D-similarity-based virtual screening

Daniel R. McMasters, Margarita Garcia-Calvo, Vladimir Maiorov, Margaret E. McCann, Roger D. Meurer, Herbert G. Bull, JeanMarie Lisnock, Kobporn L. Howell, Robert J. DeVita

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 246 KB

english, 2009

33

Multiple strategies for the preparation of a sulfur-35 labeled NPC1L1 radioligand

Joseph P. Simeone, Matthew P. Braun, Joseph F. Leone, Peter Lin, Robert J. DeVita, Margarita Garcia-Calvo, Herb G. Bull, JeanMarie Lisnock, Dennis C. Dean

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 236 KB

english, 2009

34

Spiroimidazolidinone NPC1L1 inhibitors. Part 2: Structure–activity studies and in vivo efficacy

Kobporn L. Howell, Robert J. DeVita, Margarita Garcia-Calvo, Roger D. Meurer, JeanMarie Lisnock, Herbert G. Bull, Daniel R. McMasters, Margaret E. McCann, Sander G. Mills

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 736 KB

english, 2010

35

“Identifying the hospitalised patient in crisis”—A consensus conference on the afferent limb of Rapid Response Systems

Michael A. DeVita, Gary B. Smith, Sheila K. Adam, Inga Adams-Pizarro, Michael Buist, Rinaldo Bellomo, Robert Bonello, Erga Cerchiari, Barbara Farlow, Donna Goldsmith, Helen Haskell, Kenneth Hillman, M

Journal:

Year:

2010

Language:

english

File:

PDF, 174 KB

english, 2010

36

Carbethoxynitrene : Reaction with aliphatic nitriles

Walter Lwowski, Annedore Hartenstein, Claudia deVita, Robert L. Smick

Journal:

Tetrahedron Letters

Year:

1964

Language:

english

File:

PDF, 186 KB

english, 1964

37

Synthesis of the fused bicyclic lactam-lactone terminus of neooxazolomycin by a novel dianion cyclocondensation

Andrew S Kende, Robert J DeVita

Journal:

Tetrahedron Letters

Year:

1988

Language:

english

File:

PDF, 252 KB

english, 1988

38

Novel synthesis of oxadiazoles via palladium catalysis

Jonathan R. Young, Robert J. DeVita

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 239 KB

english, 1998

39

The treatment of Hodgkin's disease

Robert C. Young, Tom Anderson, Vincent T. DeVita

Journal:

Current Problems in Cancer

Year:

1977

Language:

english

File:

PDF, 1.49 MB

english, 1977

40

Potent antagonists of gonadotropin releasing hormone receptors derived from quinolone-6-carboxamides

Thomas F Walsh, Richard B Toupence, Jonathan R Young, Song X Huang, Feroze Ujjainwalla, Robert J DeVita, Mark T Goulet, Matthew J Wyvratt Jr., Michael H Fisher, Jane-Ling Lo, Ning Ren, Joel B Yudkovit

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 168 KB

english, 2000

41

Quinolones as gonadotropin releasing hormone (GnRH) antagonists: simultaneous optimization of the C(3)-aryl and C(6)-substituents

Jonathan R. Young, Song X. Huang, Irene Chen, Thomas F. Walsh, Robert J. DeVita, Matthew J. Wyvratt Jr., Mark T. Goulet, Ning Ren, Jane Lo, Yi Tien Yang, Joel B. Yudkovitz, Kang Cheng, Roy G. Smith

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 274 KB

english, 2000

42

Benzolactam growth hormone secretagogues: Carboxamides as replacements for the 2′-tetrazole moiety of L-692,429

Robert J. DeVita, William R. Schoen, Michael H. Fisher, Alison J. Frontier, Judith M. Pisano, Matthew J. Wyvratt Jr., Kang Cheng, Wanda W.-S. Chan, Bridget S. Butler, Gerard J. Hickey, Thomas M. Jacks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 356 KB

english, 1994

43

Benzolactam growth hormone secretagogues: replacements for the 2′-tetrazole moiety of L-692,429

Robert J. DeVita, William R. Schoen, Dong Ok, Louis Barash, Jeanette E. Brown, Michael H. Fisher, Paul Hodges, Matthew J. Wyvratt Jr., Kang Cheng, Wanda W.-S. Chan, Bridge S. Butler, Roy G. Smith

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 451 KB

english, 1994

44

Structure-activity relationships of the non-peptidyl growth hormone secretagogue L-692,429

Dong Ok, William R. Schoen, Paul Hodges, Robert J. DeVita, Jeannette E. Brown, Kang Cheng, Wanda W.-S. Chan, Bridget S. Butler, Roy G. Smith, Michael H. Fisher, Matthew J. Wyvratt

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 359 KB

english, 1994

45

Identification and initial structure-activity relationships of a novel non-peptide quinolone GnRH receptor antagonist

Robert J. DeVita, Darius D. Hollings, Mark T. Goulet, Matthew J. Wyvratt, Michael H. Fisher, Jane-L. Lo, Yi Tien Yang, Kang Cheng, Roy G. Smith

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 339 KB

english, 1999

46

Investigation of the 4-O-alkylamine substituent of non-peptide quinolone GnRH receptor antagonists

Robert J. DeVita, Mark T. Goulet, Matthew J. Wyvratt, Michael H. Fisher, Jane-L. Lo, Yi Tien Yang, Kang Cheng, Roy G. Smith

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 233 KB

english, 1999

47

The effect of withdrawal of ACE inhibitors or angiotensin receptor blockers prior to coronary angiography on the incidence of contrast-induced nephropathy

Jordan L. Rosenstock, Robert Bruno, Jin K. Kim, Lev Lubarsky, Robert Schaller, Georgia Panagopoulos, Maria V. DeVita, Michael F. Michelis

Journal:

International Urology and Nephrology

Year:

2008

Language:

english

File:

PDF, 169 KB

english, 2008

48

Treatment of hodgkin's disease using intensive chemotherapy followed by irradiation

Larry E. Kun, Vincent T. Devita, Robert C. Young, Ralph E. Johnson

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1976

Language:

english

File:

PDF, 787 KB

english, 1976

49

Identification of neutral 4-O-alkyl quinolone nonpeptide GnRH receptor antagonists

Robert J. DeVita, Mamta Parikh, Jinlong Jiang, Jason A. Fair, Jonathan R. Young, Thomas F. Walsh, Mark T. Goulet, Jane-L. Lo, Ning Ren, Joel B. Yudkovitz, Jisong Cui, Yi T. Yang, Kang Cheng, Susan P.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 287 KB

english, 2004

50

A mild four-carbon homologation of aldehydes to E,E-dienamines

Andrew S. Kende, Robert J. DeVita

Journal:

Tetrahedron Letters

Year:

1990

Language:

english

File:

PDF, 208 KB

english, 1990